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KMID : 0362919840020010033
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1984 Volume.2 No. 1 p.33 ~ p.39
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Radiation Therapy for Brain Metastases
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Kim Il-Han
Park Charn-Il
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Abstract
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One hundred and twenty patients with brain metastases were seen and evaluated in the Dept. of Therapeutic Radiology, Seoul National University Hospital between 1797 and 1983. Of these, 90 patients received whole brain irradiation with 2,000 rad in 1 week or 3,000 rad in 2 weeks for palliative purpose and 30 patients failed to complete the planned treatment.
Carcinoma of the lung(44 cases), choriocarcinoma(11 cases), breast(8 cases) were common primary tumors of 90 patients receiving planned treatment.
Symptomatic subjective response was obtained in 92% of patients and neurologic functional improvement was obtained in 42% of patients.
Median survival was 6.4 months in patients with complete treatment and less than 2 months in patients with incomplete treatment, overall survival rate at 1 year and 2 year were 26%, 16% in patients with complete treatment and 8%, 0% in patients with incomplete treatment.
Primary site, extent of metastases and interval from diagnosis of primary tumor to brain metastases were identified as prognostic factors.
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KEYWORD
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